Association between body mass index (BMI) and [ 123 I]Ioflupane (DaTSCAN) availabilities in patients with parkinsonism using single-photon emission computed tomography-computed tomography (SPECT-CT).

Puja ParekhPatrick BegleyMaryam JessopMark AplinElena MissirHelena McMeekinGosia RaczekNitasha SinghSabina Dizdarevic

Published in: European journal of hybrid imaging (2023)

Absolute NC values demonstrate a strong inverse correlation with BMI, strongest in the extrastriatal regions. Due to the predominately non-overlapping distribution of DaT and SERT, this study suggests greater involvement of SERT in obesity with possible interplay with DA transmission.

Keyphrases

computed tomography
body mass index
weight gain
dual energy
positron emission tomography
image quality
contrast enhanced
magnetic resonance imaging
insulin resistance
metabolic syndrome
type diabetes
weight loss
pet ct
magnetic resonance
parkinson disease
drug induced