Altered mRNA Expression of NFKB1 and NFKB2 Genes in Penile Lichen Sclerosus, Penile Cancer and Zoon Balanitis.

Piotr Mieczyslaw Wierzbicki Mateusz CzajkowskiAnna Kotulak-ChrząszczJustyna BukowiczKlaudia DzieciuchMałgorzata Sokołowska-Wojdyło Zbigniew Kmieć Matuszewski Marcin

Published in: Journal of clinical medicine (2022)

This is the first study regarding gene profiles of NFKB1/2 in PC and penile dermatoses. New drugs targeting modulation of canonical-activated NF-κB pathway should be studied and introduced to the treatment of PLS and PC apart from other treatments.

Keyphrases

genome wide
radical prostatectomy
genome wide identification
papillary thyroid
signaling pathway
prostate cancer
oxidative stress
lps induced
squamous cell
cancer therapy
dna methylation
gene expression
nuclear factor
cell proliferation
inflammatory response
drug induced