Assessment of mouse-specific pharmacokinetics in kidneys based on 131 I activity measurements using micro-SPECT.

Clarita Saldarriaga VargasLara StruelensMatthias D'HuyvetterVicky CaveliersPeter Covens

Published in: EJNMMI physics (2022)

I-labelled sdAb in mouse kidneys. This opens the possibility to perform mouse-specific kidney-tissue dosimetry based on pharmacokinetic data acquired in vivo on the same mice used in nephrotoxicity studies.

Keyphrases

metabolic syndrome
big data
pet ct
drug induced