Stroke in Pregnancy and Preeclampsia: Effect of Low-Dose Aspirin Treatment on Collateral Flow Velocity and Cerebral Blood Flow Autoregulation During Ischemia in Rats.
Marilyn J CipollaSarah M TremblePublished in: Journal of the American Heart Association (2024)
Low-dose aspirin in ePE reduced infarction that was associated with increased vasodilator prostacyclin and improved collateral perfusion during induced hypertension. The beneficial effect of aspirin on the brain and cerebral circulation is likely multifactorial and worth further study.
Keyphrases
- low dose
- cerebral blood flow
- high dose
- blood pressure
- cerebral ischemia
- atrial fibrillation
- pregnancy outcomes
- early onset
- pulmonary arterial hypertension
- preterm birth
- white matter
- magnetic resonance imaging
- resting state
- cardiovascular disease
- computed tomography
- contrast enhanced
- acute coronary syndrome
- combination therapy
- antiplatelet therapy
- replacement therapy