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Activation of hepatic stellate cell in Pten null liver injury model.

Lina HeJames GubbinsZhechu PengVivian MedinaFan FeiKinji AsahinaJiaohong WangMichael KahnCarl B RountreeBangyan L Stiles
Published in: Fibrogenesis & tissue repair (2016)
Wnt/β-catenin activation serves as an important mediator for fibrosis development resulting from NASH using a mouse model where NASH is mimicked by PTEN loss.
Keyphrases
  • liver injury
  • cell proliferation
  • drug induced
  • mouse model
  • pi k akt
  • single cell
  • epithelial mesenchymal transition
  • stem cells
  • cell therapy
  • signaling pathway
  • bone marrow