Opioid analgesia and severity of acute pancreatitis: An international multicentre cohort study on pain management in acute pancreatitis.

Sanjay Pandanaboyana Cecilie Siggaard Knoph Søren Schou OlesenMichael JonesJames LucocqJayanta SamantaRupjyoti Talukdar Gabriele Capurso Enrique de MadariaDhiraj YadavAjith K SiriwardenaJohn WindsorAsbjørn Mohr DrewesManu Nayarnull null

Published in: United European gastroenterology journal (2024)

Opioid treatment increased the risk of more severe acute pancreatitis only when administered after admission day or for 6 days or more. Future randomised studies should re-evaluate whether opioids might be safe in acute pancreatitis.

Keyphrases

pain management
chronic pain
clinical trial
study protocol
emergency department
double blind
early onset
case control
drug induced