IGF-1 TMJ injections enhance mandibular growth and bone quality in juvenile rats.

Ashwini S JoshiNan E HatchTakayuki HayamiAndrew H Jheon Sunil D Kapila

Published in: Orthodontics & craniofacial research (2021)

Local administration of high-dose 80 µg/kg IGF-1 enhances mandibular growth and condylar bone quality and quantity in growing rats. The findings have implications for modulating mandibular growth and potentially enhancing condylar bone health and integrity.

Keyphrases

high dose
bone mineral density
soft tissue
public health
healthcare
bone loss
bone regeneration
low dose
signaling pathway
binding protein
postmenopausal women
quality improvement
pi k akt
growth hormone