Progressive outer retinal necrosis-like retinitis in immunocompetent hosts.
Rohan ChawlaKoushik TripathyVarun GogiaPradeep VenkateshPublished in: BMJ case reports (2016)
We describe two young immunocompetent women presenting with bilateral retinitis with outer retinal necrosis involving posterior pole with centrifugal spread and multifocal lesions simulating progressive outer retinal necrosis (PORN) like retinitis. Serology was negative for HIV and CD4 counts were normal; however, both women were on oral steroids at presentation for suspected autoimmune chorioretinitis. The retinitis in both eyes responded well to oral valaciclovir therapy. However, the eye with the more fulminant involvement developed retinal detachment with a loss of vision. Retinal atrophy was seen in the less involved eye with preservation of vision. Through these cases, we aim to describe a unique evolution of PORN-like retinitis in immunocompetent women, which was probably aggravated by a short-term immunosuppression secondary to oral steroids.
Keyphrases
- optical coherence tomography
- diabetic retinopathy
- polycystic ovary syndrome
- multiple sclerosis
- optic nerve
- pregnancy outcomes
- cervical cancer screening
- hiv infected
- breast cancer risk
- antiretroviral therapy
- human immunodeficiency virus
- hiv positive
- type diabetes
- pulmonary embolism
- hepatitis c virus
- stem cells
- hiv aids
- insulin resistance
- adipose tissue
- skeletal muscle
- middle aged
- nk cells
- cell therapy