Granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α in combination is a useful diagnostic biomarker to distinguish familial Mediterranean fever from sepsis.

Tomohiro KogaKaori FurukawaKiyoshi MigitaShimpei MorimotoToshimasa ShimizuShoichi FukuiMasataka UmedaYushiro EndoRemi SumiyoshiShin-Ya KawashiriNaoki IwamotoKunihiro IchinoseMami TamaiTomoki OriguchiTakahiro MaedaAkihiro YachieAtsushi Kawakami

Published in: Arthritis research & therapy (2021)

Determination of GM-CSF and TNF-α levels in combination may represent a biomarker for the differential diagnosis of FMF from sepsis, based on measurement of multiple cytokines.

Keyphrases

septic shock
rheumatoid arthritis
acute kidney injury
intensive care unit
adipose tissue
early onset
peripheral blood
solid phase extraction
mass spectrometry
recombinant human