Granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α in combination is a useful diagnostic biomarker to distinguish familial Mediterranean fever from sepsis.
Tomohiro KogaKaori FurukawaKiyoshi MigitaShimpei MorimotoToshimasa ShimizuShoichi FukuiMasataka UmedaYushiro EndoRemi SumiyoshiShin-Ya KawashiriNaoki IwamotoKunihiro IchinoseMami TamaiTomoki OriguchiTakahiro MaedaAkihiro YachieAtsushi KawakamiPublished in: Arthritis research & therapy (2021)
Determination of GM-CSF and TNF-α levels in combination may represent a biomarker for the differential diagnosis of FMF from sepsis, based on measurement of multiple cytokines.