Talabostat Alleviates Obesity and Associated Metabolic Dysfunction via Suppression of Macrophage-Driven Adipose Inflammation.

Yunyun WuTiancong ShiJiqiu WangRui He

Published in: Obesity (Silver Spring, Md.) (2020)

Our study demonstrates that TB at a low dose could increase energy expenditure and control ATM-mediated adipose inflammation in obese mice, thereby alleviating obesity and its associated metabolic dysfunction.

Keyphrases

insulin resistance
oxidative stress
adipose tissue
low dose
metabolic syndrome
weight loss
high fat diet induced
type diabetes
dna damage
weight gain
mycobacterium tuberculosis
body mass index
mouse model
dna damage response
physical activity