Health-related quality of life in pre-school age children with single-ventricle CHD.
Kristina N HeyeWalter KnirschIanina ScheerIngrid BeckKristina WetterlingAndreas HahnKaroline HofmannBeatrice LatalBettina ReichMarkus A LandoltPublished in: Cardiology in the young (2019)
Health-related quality of life in pre-schoolers with single-ventricle CHD was comparable to children with biventricular CHD. Preterm birth and perioperative variables were significant predictors of low health-related quality of life. Notably, pre-Fontan brain MRI findings and neurodevelopmental status were not associated with health-related quality of life. Overall, perioperative variables explained 24% of the variability of the total health-related quality of life score.InterpretationDespite substantial health-related burden, pre-schoolers with single-ventricle CHD showed good health-related quality of life. Less-modifiable treatment-related risk factors and preterm birth had the highest impact on health-related quality of life. Long-term follow-up assessment of self-reported health-related quality of life is needed to identify patients with poorer health-related quality of life and to initiate supportive care.
Keyphrases
- preterm birth
- low birth weight
- risk factors
- gestational age
- pulmonary artery
- pulmonary hypertension
- mitral valve
- young adults
- cardiac surgery
- patients undergoing
- healthcare
- magnetic resonance imaging
- congenital heart disease
- palliative care
- white matter
- pain management
- magnetic resonance
- computed tomography
- acute kidney injury
- preterm infants
- quality improvement
- smoking cessation
- health insurance