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Integrated Network Pharmacology Analysis and Experimental Validation to Reveal the Mechanism of Anti-Insulin Resistance Effects of Moringa oleifera Seeds.

Qiong HuangRong LiuJing LiuQi HuangManhua LiuYueping Jiang
Published in: Drug design, development and therapy (2020)
Our study successfully predicts the active ingredients and potential targets of MOS for improving IR and helps to illustrate mechanism of action at a systemic level. This study not only provides new insights into the chemical basis and pharmacology of MOS but also demonstrates a feasible method for discovering potential drugs from traditional medicines.
Keyphrases
  • insulin resistance
  • quantum dots
  • type diabetes
  • metabolic syndrome
  • gene expression
  • risk assessment
  • skeletal muscle
  • human health
  • gold nanoparticles
  • glycemic control
  • high fat diet induced