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Clinical Germline Testing Results of Men With Prostate Cancer: Patient-Level Factors and Implications of NCCN Guideline Expansion.

Samantha E GreenbergTrevor C HuntJacob P AmbroseWilliam T LowranceChristopher B DechetBrock B O'NeilJonathan D Tward
Published in: JCO precision oncology (2021)
This study demonstrated a stable PV detection rate in men with PC using expanded criteria aligned to the updated NCCN testing guidelines. However, we did not find strong evidence to suggest that patient-level factors are associated with PV germline testing results. These findings support the recent expansion of NCCN germline testing guidelines in PC.
Keyphrases
  • prostate cancer
  • dna repair
  • case report
  • clinical practice
  • radical prostatectomy
  • oxidative stress
  • label free