Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.

Lingfei LiYanhai FengJunhui ZhangQiong ZhangJun RenCheng SunShujing LiXia LeiGaoxing LuoJiongyu HuYuesheng Huang

Published in: Cell communication and signaling : CCS (2022)

The findings indicated a novel role for p-MAP4 in causing proteinuria in DN. Our results indicated the therapeutic potential of MAP4 in protecting against proteinuria and related diseases. Video Abstract.

Keyphrases

diabetic nephropathy
high glucose
diabetic rats
high density
drug induced
endothelial cells