Incidence of Micrometastasis and Isolated Tumour Cells in Clinicopathologically Node-Negative Head and Neck Squamous Cell Carcinoma.

Kinjal Shankar MajumdarVishal U S RaoRachana PrasadVeena RamaswamyPiyush SinhaAnand Subash

Published in: Journal of maxillofacial and oral surgery (2019)

Micrometastasis and isolated tumour cells are found in approximately 9% of cases of early-stage oral cavity squamous cell carcinoma. The predictive factors and clinical significance are still unknown. More prospective trials are required to solve this evolving aspect of HNSCC.

Keyphrases

induced apoptosis
squamous cell carcinoma
early stage
cell cycle arrest
endoplasmic reticulum stress
risk factors
signaling pathway
cell proliferation
lymph node metastasis
radiation therapy
pi k akt
neoadjuvant chemotherapy