Association between duration of antimicrobial prophylaxis and postoperative outcomes after lumbar spine surgery.
Mary W PorterWilliam BurdiJonathan D CasavantMcKenna C EastmentLuis Gonzaga TullochPublished in: Infection control and hospital epidemiology (2022)
Longer courses of AMP after lumbar spine surgery were associated with higher odds of CDI, prolonged hospitalization, and reoperation, but not with lower odds of SSI. However, adherence to the recommended duration of AMP is very low, hinting at a wide evidence-to-practice gap that needs to be addressed by spine surgeons and antimicrobial stewardship programs.