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Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice.

Ann E WellsJohn J WilsonSarah E HeuerJohn D SearsJian WeiRaghav PandeyMauro W CostaCatherine C KaczorowskiDerry C RoopenianChih-Hao ChangGregory W Carter
Published in: PloS one (2024)
These findings suggest that 2DG has a systemic impact that varies across organs, potentially affecting multiple pathways and functions. The study provides insights into the potential therapeutic benefits of 2DG across different diseases and highlights the importance of understanding its systemic effects for future research and clinical applications.
Keyphrases
  • current status
  • type diabetes
  • computed tomography
  • combination therapy
  • adipose tissue
  • drug induced
  • skeletal muscle
  • smoking cessation