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A rare case of multiple variants of porokeratosis in the same patient: The clue of dermoscopy for diagnosis and therapeutical update.

Renan Tironi Giglio de OliveiraFernanda S SimonetiGiovana L P L AgostinhoBeatrice M Z AbdallaDaniela S LocatelliThais PincelliPaulo R Criado
Published in: Dermatologic therapy (2020)
Porokeratosis (PK) consists of abnormal keratinization of the epidermis of uncertain etiology and was first described by Mibelli in 1893. Multiple clinical variants of porokeratosis are recognized. The following is a case of a young male who presented more than one form of PK simultaneously. The hallmark of PK is the cornoid lamella, which can be identified in histopathology, and sometimes, as in our case, dermoscopy examination is the clue for diagnosis. This condition is often misdiagnosed and, therefore, not appropriately treated. Several treatment options are available and each clinical form may respond better to a specific therapy. However, consistency in treatment guidelines is still lacking.
Keyphrases
  • rare case
  • copy number
  • case report
  • gene expression
  • dna methylation
  • bone marrow
  • middle aged
  • cell therapy