Does the accumulated antiepileptic drug load in chronic epilepsy reflect disease severity?
Juri-Alexander WittRobert Daniel NassTobias BaumgartnerRandi von WredeChristian E ElgerRainer SurgesChristoph HelmstaedterPublished in: Epilepsia (2020)
Clinical markers of epilepsy severity were only marginally associated with drug load. Findings rather indicate that patients seem to accumulate drugs due to the chronicity of epilepsy. Overall, the drug load remained largely unexplained. The findings nevertheless call for scrutinizing multidrug therapies in patients with long-lasting epilepsies.