Targeting of endothelial cells in brain tumours.
Wenzhe DuanShengkai XiaMengyi TangManqing LinWenwen LiuQi WangPublished in: Clinical and translational medicine (2023)
Interventions targeting ECs, as an adjunct to other therapies (e.g. immunotherapies, molecular-targeted therapies), have shown promising clinical efficacy due to the high degree of vascularisation in brain tumours. Developing precise strategies to target tumour-associated vessels based on the heterogeneity of ECs is expected to improve anti-vascular efficacy.