Lower blood pH as a strong prognostic factor for fatal outcomes in critically ill COVID-19 patients at an intensive care unit: A multivariable analysis.
Martin KieningerAnnemarie SinningTimea VadászMichael GruberWolfram GronwaldFlorian ZemanDirk LunzThomas DienemannStephan SchmidBernhard GrafMatthias LubnowThomas MüllerThomas HolzmannBernd SalzbergerBärbel KieningerPublished in: PloS one (2021)
Within the cohort, 19 patients died (mortality 32.2%). Blood pH value, mean arterial pressure, base excess, troponin, and procalcitonin were identified as highly significant prognostic factors of in-hospital mortality. However, no significant differences were found for other parameters expected to be relevant prognostic factors, like low arterial partial pressure of oxygen or high lactate levels. In the multivariable logistic regression analysis, the pH value and the mean arterial pressure turned out to be the most influential prognostic factors for a lethal course.