Conditions for modifying intraocular lenses as drug carriers for methotrexate using poly (lactic-co-glycolic acid).
Clarissa BillStefan KassumehChristina HilterhausNatalie TersiArne J SpeidelAndreas OhlmannSiegfried PriglingerClaudia PriglingerArmin WolfChristian Maximilian WertheimerPublished in: European journal of ophthalmology (2024)
After determination of the required physicochemical manufacturing conditions, a drug releasing IOL was designed. A favourable release profile in an ocular pharmacokinetics model could be shown.