A multi-omics approach to overeating and inactivity-induced muscle atrophy in db/db mice.

Takuro OkamuraMasahide HamaguchiGenki KobayashiTakahiro IchikawaYuka HasegawaTomoki MiyoshiTakafumi SenmaruNaoko NakanishiRyoichi SasanoMichiaki Fukui

Published in: Journal of cachexia, sarcopenia and muscle (2024)

The multi-omics approach provided insights into the epigenomic alterations in the small intestine, suggesting their involvement in the pathogenesis of inactivity-induced muscle atrophy in obese mice.

Keyphrases

high glucose
diabetic rats
skeletal muscle
single cell
drug induced
oxidative stress
type diabetes
adipose tissue