Decellularized Vascular Scaffolds Derived from Bovine Placenta Blood Vessels.

Tarley Santos OliveiraIgor SmirnowKadija Mohamed SanteeMaria Angelica Miglino Rodrigo da Silva Nunes Barreto

Published in: Arquivos brasileiros de cardiologia (2023)

The decellularization process produced vessels that maintained natural structure and elastin content, and no cells or gDNA remains were observed. Endothelial precursor cells were also attached to lumen and external surface of the decellularized vessel.Conclusion: Our results show a possibility of future uses of this biomaterial in cardiovascular medicine, as in the development of engineered vessels.

Keyphrases

induced apoptosis
tissue engineering
cell cycle arrest
extracellular matrix
endoplasmic reticulum stress
cell death
oxidative stress
current status