Aziridine Ring Opening as Regio- and Stereoselective Access to C -Glycosyl-Aminoethyl Sulfide Derivatives.

A short synthetic route to stereoselective access to C -glycosyl-aminoethyl sulfide derivatives has been developed through the reaction of tributhyltin derivatives of glycals with aziridinecarboaldehyde and the regioselective ring opening of a chiral aziridine with thiophenol. The absolute configurations of the resulting diastereoisomers were determined by 1H NMR spectroscopy.