Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in db/db mice.

Huy PhoSlava BergerCarla FreireLenise J KimMi-Kyung ShinStone R StreeterNishitha HosamaneMeaghan E CabassaFrederick Anokye-DansoOlga DergachevaMateus R AmorimThomaz Fleury-CuradoJonathan C JunAlan R SchwartzRexford S AhimaDavid MendelowitzVsevolod Y Polotsky

Published in: Sleep (2021)

Leptin stimulates breathing and treats obesity hypoventilation acting on LepRb-positive neurons in the DMH.

Keyphrases

high fat diet induced
insulin resistance
metabolic syndrome
weight loss
type diabetes
spinal cord
physical activity
weight gain
prefrontal cortex
sleep quality
positive airway pressure
depressive symptoms
obstructive sleep apnea
wild type
spinal cord injury
skeletal muscle
body mass index