Genetic, Electrophysiological, and Pathological Studies on Patients with SCN9A-related Pain Disorders.

Jun-Hui YuanXiaoyang ChengEiji MatsuuraYujiro HiguchiMasahiro AndoAkihiro HashiguchiAkiko YoshimuraRyo NakachiJun MineTakeshi TaketaniKenichi MaedaSaori KawakamiRyutaro KiraShoko TanakaKazuaki KanaiFadia Dib-HajjSulayman D Dib-HajjStephen G WaxmanHiroshi Takashima

Published in: Journal of the peripheral nervous system : JPNS (2023)

Clinical features observed in our patients broaden the phenotypic spectrum of SCN9A-related pain disorders, and the electrophysiological analysis enriches the understanding of genotype-phenotype association caused by Nav1.7 gain-of-function mutations. This article is protected by copyright. All rights reserved.

Keyphrases

chronic pain
end stage renal disease
pain management
ejection fraction
neuropathic pain
newly diagnosed
peritoneal dialysis
prognostic factors
dna methylation
case control