Login / Signup

Whole-genome analyses reveal a novel prophage and cgSNPs-derived sublineages of Brachyspira hyodysenteriae ST196.

Ana Belén García-MartínThomas RoderSarah SchmittFriederike ZeehRémy BruggmannVincent Perreten
Published in: BMC genomics (2022)
This study contributes to the catalogue of publicly available genomes and provides relevant bioinformatic tools and information for further comparative genomic analyses for B. hyodysenteriae. It reveals that Swiss B. hyodysenteriae isolates of the same ST may have evolved independently over time by point mutations and acquisition of larger genetic elements. In line with this, the third type of mobile genetic element described so far in B. hyodysenteriae, the novel prophage pphBhCH20, has been identified in a single isolate of B. hyodysenteriae of ST196.
Keyphrases
  • genome wide
  • copy number
  • dna methylation
  • gene expression
  • healthcare