Longitudinal Assessment of Creatine Kinase, Creatine/Creatinine ratio , and Myostatin as Monitoring Biomarkers in Becker Muscular Dystrophy.

Nienke M van de VeldeZaïda KoeksMirko SignorelliNisha VerweyMaurice Overzier Jaap Adriaan Bakker Gautam SajeevJames SignorovitchValeria Ricotti Jan J G M Verschuuren Kristy Brown Pietro Spitali Erik H Niks

Published in: Neurology (2022)

Both Cr/Crn and myostatin could potentially serve as monitoring biomarkers in BMD, as higher Cr/Crn and lower myostatin were associated with lower motor performance and predictive of concurrent functional performance when combined with age. Future studies are needed to more precisely determine the context of use of these biomarkers.

Keyphrases

muscular dystrophy
duchenne muscular dystrophy
uric acid
metabolic syndrome
current status
radiation therapy
case control
rectal cancer