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Is obstructive sleep apnea associated with erythrocytosis? A systematic review and meta-analysis.

Min-Seok RhaYeonsu JeongJungghi KimChang Hoon KimJoo-Heon YoonHyung-Ju Cho
Published in: Laryngoscope investigative otolaryngology (2022)
Our meta-analysis revealed that the hematocrit value was significantly increased in patients with OSA, particularly in severe patients, compared with that in controls. However, the elevation was modest, and the hematocrit value is expected to be within the normal range in patients with OSA. These data suggest that OSA leads to slight increases in hematocrit but does not cause clinically significant erythrocytosis.
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