SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes.

Leslie CalapreElin S GraySandrine KurdykowskiAnthony DavidPascal DescarguesMel Ziman

Published in: BMC dermatology (2017)

This study demonstrate that heat-induced SIRT1 activation mediates survival of DNA damaged keratinocytes through deacetylation of p53 after exposure to UVB plus heat.

Keyphrases

heat stress
diabetic rats
high glucose
oxidative stress
drug induced
ischemia reperfusion injury
free survival
single molecule
circulating tumor
wound healing
cell free
stress induced