The impact of mitochondria-related POLG and TFAM variants on breast cancer pathomorphological characteristics and patient outcomes.

Ieva StakaitieneRasa UgenskieneErika KorobeinikovaJurgita GudaitieneDomas VaitiekusLina PoskieneElona Juozaityte

Published in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2021)

Our data suggest that variations in POLG and TFAM genes are important determinacies of tumour phenotype and disease outcome in breast cancer patients.

Keyphrases

electronic health record
genome wide
copy number
cell death
big data
reactive oxygen species
bioinformatics analysis
dna methylation
machine learning
data analysis
young adults