Hypogeusia as the initial presenting symptom of COVID-19.
Lauren E MelleyEli BressErik PolanPublished in: BMJ case reports (2020)
COVID-19 is the disease caused by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first arose in Wuhan, China, in December 2019 and has since been declared a pandemic. The clinical sequelae vary from mild, self-limiting upper respiratory infection symptoms to severe respiratory distress, acute cardiopulmonary arrest and death. Otolaryngologists around the globe have reported a significant number of mild or otherwise asymptomatic patients with COVID-19 presenting with olfactory dysfunction. We present a case of COVID-19 resulting in intensive care unit (ICU) admission, presenting with the initial symptom of disrupted taste and flavour perception prior to respiratory involvement. After 4 days in the ICU and 6 days on the general medicine floor, our patient regained a majority of her sense of smell and was discharged with only lingering dysgeusia. In this paper, we review existing literature and the clinical course of SARS-CoV-2 in relation to the reported symptoms of hyposmia, hypogeusia and dysgeusia.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- intensive care unit
- coronavirus disease
- case report
- mechanical ventilation
- respiratory tract
- emergency department
- oxidative stress
- drug induced
- sleep quality
- respiratory failure
- early onset
- acute respiratory distress syndrome
- cell cycle
- patient reported
- physical activity
- depressive symptoms
- hepatitis b virus
- aortic dissection