Small RNA sequencing reveals snoRNAs and piRNA-019825 as novel players in diabetic kidney disease.
Leendert M 't HartJ A de KlerkG A BoulandJ H D PeerlingsM T BlomS J CramerR BijkerkJ W J BeulensR C SliekerPublished in: Endocrine (2024)
We have identified novel small non-coding RNAs, primarily from classes other than microRNAs, that are associated with diabetic kidney disease. Our results show that the involvement of small non-coding RNAs in DKD goes beyond the already known microRNAs and also involves other classes of sncRNA, in particular snoRNAs and the piRNA piR-019825, that have never been studied before in relation to kidney function.
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