CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer.

Hui ZhangXingyuan XiaoWenjie WeiChao HuangMiao WangLiang WangYuanqiao HeJiayin SunYangkai JiangGuosong JiangXiaoping Zhang

Published in: Molecular cancer (2021)

CircLIFR could interact with MSH2 to positively modulate CDDP-sensitivity through MutSα/ATM-p73 axis in bladder cancer. CircLIFR and MSH2 might be act as promising therapeutic targets for CDDP-resistant bladder cancer.

Keyphrases

dna damage
dna repair
dna damage response
oxidative stress