Calmodulin inhibitor ameliorates cognitive dysfunction via inhibiting nitrosative stress and NLRP3 signaling in mice with bilateral carotid artery stenosis.

Rui WangYi-Xuan YinQaisar MahmoodXiao-Juan WangYin-Ping GaoGuo-Jing GouMuhammad Masood AhmedFukunag KohjiYong-Zhong DuFeng Han

Published in: CNS neuroscience & therapeutics (2017)

These data disclose novel findings about the therapeutic potential of DY-9836, and its encapsulated nanodrug delivery system significantly enhanced the cognitive function via inhibitory effect on nitrosative stress and NLRP3 signaling in VaD mice.

Keyphrases

high fat diet induced
signaling pathway
nlrp inflammasome
electronic health record
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machine learning
heat stress
adipose tissue
artificial intelligence
skeletal muscle
deep learning