Oncological Outcomes for Patients Harboring Positive Surgical Margins Following Radical Cystectomy for Muscle-Invasive Bladder Cancer: A Retrospective Multicentric Study on Behalf of the YAU Urothelial Group.
Gautier MarcqLuca AfferiYann NeuzilletTimo NykoppCharlotte S VoskuilenMarc A FurrerWassim KassoufAtiqullah AzizAnne Sophie BajeotMario Álvarez-MaestroPeter BlackMorgan RoupretAidan P NoonRoland SeilerKees HendricksenMathieu RoumiguiéKarl H PangPaul Laine-CaroffEvanguelos XylinasGuillaume PloussardMarco MoschiniPaul Sargosnull nullPublished in: Cancers (2022)
Patients with PSMs following RC have poor outcomes since half of them will recur within a year and will die of their disease. Among all PSMs types, patients with multifocal PSMs harbor the worst prognosis. We observed a benefit of adjuvant chemotherapy, but clinical trials evaluating innovative adjuvant strategies for these patients remain an unmet need.