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The Immunological Profile of Adipose Mesenchymal Stromal/Stem Cells after Cell Expansion and Inflammatory Priming.

Karolien BuylMakram MerimiRobim Marcelino RodriguesSaida RahmaniMohammad Fayyad-KazanFatima BouhtitNoureddine BoukhatemTamara VanhaeckeHassan FahmiJoery De KockMehdi Najar
Published in: Biomolecules (2024)
AT-MSCs may sense and actively respond to tissue challenges by modulating distinct and specific pathways to create an appropriate immuno-reparative environment. These mechanisms need to be further characterized to identify and assess a molecular target that can enhance or impede the therapeutic ability of AT-MSCs, which therefore will help improve the quality, safety, and efficacy of the therapeutic strategy.
Keyphrases
  • signaling pathway
  • stem cells
  • mesenchymal stem cells
  • bone marrow
  • cell therapy
  • umbilical cord
  • single cell
  • adipose tissue
  • insulin resistance
  • type diabetes
  • single molecule
  • quality improvement