Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults.

Joshua M SchrockDaniel T RyanRana SaberNanette BenbowLauren A VaughtNina ReiserMatthew P VelezRyan HsiehMichael NewcombAlexis R DemonbreunBrian S MustanskiElizabeth M McNallyRichard D'AquilaThomas W McDade

Published in: medRxiv : the preprint server for health sciences (2021)

Magnitude of SARS-CoV-2 virus exposure may contribute to symptom severity. In a sample of seropositive adults (n=1101), we found that individuals who lived with a known COVID-19 case exhibited greater symptom severity and IgG concentrations compared to individuals who were seropositive but did not live with a known case (P<0.0001).

Keyphrases

sars cov
respiratory syndrome coronavirus
patient reported
coronavirus disease
disease virus