Acetaminophen impairs ferroptosis in the hippocampus of septic mice by regulating glutathione peroxidase 4 and ferroptosis suppressor protein 1 pathways.
Jing ChuHong LiZhihao YuanWenyu ZhouYang YuYonghao YuPublished in: Brain and behavior (2023)
These data suggest that APAP inhibits ferroptosis in the cerebral hippocampus of septic mice through the GPX4 and FSP1 pathways.
Keyphrases
- cell death
- high fat diet induced
- acute kidney injury
- cerebral ischemia
- subarachnoid hemorrhage
- cognitive impairment
- prefrontal cortex
- electronic health record
- hydrogen peroxide
- insulin resistance
- nitric oxide
- blood brain barrier
- metabolic syndrome
- binding protein
- machine learning
- amino acid
- brain injury
- artificial intelligence
- cerebral blood flow