Near-Infrared Light-Excited Reactive Oxygen Species Generation by Thulium Oxide Nanoparticles.
Dida DuosikenRuihao YangYingfan DaiZeinab MarfaviQuanjie LvHanyin LiKang SunKe TaoPublished in: Journal of the American Chemical Society (2022)
Exploring materials that can absorb near-infrared (NIR) light to produce reactive oxygen species (ROS) is necessary for many fields. Herein we show that thulium oxide nanoparticles are viable for NIR-stimulated ROS generation. This property may be related to the unique energy levels, large absorption cross section, low fluorescence emission, and ∼10 -3 s lifetime of the 3 H 4 state of Tm ions. We further demonstrate the impact of these nanoparticles on photodynamic therapy (PDT), in which impressive tumor inhibition was recorded after exposure to either a broadband halogen lamp or an 808 nm laser. Our results may provide insight into the areas of photocatalysis, pollution treatment, and fine chemical synthesis.
Keyphrases
- reactive oxygen species
- photodynamic therapy
- oxide nanoparticles
- fluorescence imaging
- heavy metals
- high speed
- risk assessment
- air pollution
- particulate matter
- energy transfer
- single molecule
- human health
- climate change
- loop mediated isothermal amplification
- drug delivery
- drug induced
- smoking cessation
- drinking water
- water quality