CDK12 orchestrates super-enhancer-associated CCDC137 transcription to direct hepatic metastasis in colorectal cancer.
Wei DaiJunhong WuXiaopeng PengWen HouHao HuangQilai ChengZhiping LiuWalter LuytenLiliane SchoofsJingfeng ZhouSheng-Lan LiuPublished in: Clinical and translational medicine (2022)
Our data highlight the potential of CDK12 and SE-associated oncogenic transcripts as therapeutic targets for patients with liver metastatic CRC.