Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.

Fan LiuZhiyao WangYue QiuMin WeiChunyan LiYikuan XieLe ShenYuguang HuangChao Ma

Published in: Journal of neuroinflammation (2017)

MyD88-dependent TIR pathway in the DRG and SDH may play a role in CCI-induced neuropathic pain. MyD88 might serve as a potential therapeutic target for neuropathic pain.

Keyphrases

neuropathic pain
peripheral nerve
spinal cord
spinal cord injury
toll like receptor
high glucose
oxidative stress
diabetic rats
inflammatory response
mouse model
immune response
endothelial cells