Time to deterioration in cancer randomized clinical trials for patient-reported outcomes data: a systematic review.

Emilie ChartonB CuerF CottoneF EfficaceC TouraineZ HamidouF FiteniF BonnetainM-C Woronoff-LemsiC Bascoul-MolleviA Anota

Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2019)

This review highlights the lack of standardization of the TTD approach for the analysis of PRO data in RCTs. Special attention should be paid to the definition of "deterioration", and this should be based on the specific cancer setting.

Keyphrases

patient reported outcomes
papillary thyroid
squamous cell
electronic health record
big data
working memory
squamous cell carcinoma
lymph node metastasis
machine learning
anti inflammatory
artificial intelligence
data analysis
deep learning