Genetic susceptibility to asthma increases the vulnerability to indoor air pollution.
Anke HülsAneesa VankerDiane GrayNastassja KoenJulia L MacIsaacDavid T S LinKatia E RamadoriPeter D SlyDan J SteinMichael S KoborHeather J ZarPublished in: The European respiratory journal (2020)
PM10 and maternal smoking exposures were associated with reduced lung function, with a higher susceptibility for infants with an adverse genetic predisposition for asthma that also depended on the infant's ancestry.
Keyphrases
- lung function
- air pollution
- particulate matter
- genome wide
- copy number
- climate change
- chronic obstructive pulmonary disease
- smoking cessation
- emergency department
- birth weight
- dna methylation
- risk assessment
- electronic health record
- genome wide association study
- allergic rhinitis
- drinking water
- genome wide association