Assessment of Leptomeningeal Carcinomatosis Diagnosis, Management and Outcomes in Patients with Solid Tumors Over a Decade of Experience.
Hannah N RinehardtMahmoud KassemEvan MorganMarilly PalettasJulie A StephensAnupama SureshAkaansha GanjuMaryam B LustbergRobert WesolowskiSagar D SardesaiDaniel G StoverJeffrey Bryan VanDeusenMathew Amprayil CherianMaria Del Pilar Guillermo Prieto EiblAbdul MiahIyad AlnahhasPierre GiglioVinay K PuduvalliBhuvaneswari RamaswamyNicole WilliamsAnne M NoonanPublished in: European journal of breast health (2021)
Despite improved treatments and targeted therapies, outcomes of LMC remain extremely poor. Positive CSF cytology was associated with lower OS in patients who had cytology assessed and specifically in patients with breast cancer. CSF cytology serves as an important indicator for prognosis and helps aid in developing individualized therapeutic strategies for patients with LMC.