Increased Prevalence of Familial Autoimmune Disease in Children With Opsoclonus-Myoclonus Syndrome.

Jonathan D SantoroLauren M KerrRachel CoddenTheron Charles CasperBenjamin M GreenbergEmmanuelle WaubantSek Won Kong Kenneth D MandlMark P Gorman

Published in: Neurology(R) neuroimmunology & neuroinflammation (2021)

In a cohort of pediatric patients with OMS, there were elevated rates of first-degree relative autoimmune disease, with no difference in rates observed between paraneoplastic and idiopathic etiologies, suggesting an autoimmune genetic contribution to the development of OMS in children.

Keyphrases

multiple sclerosis
young adults
drug induced
risk factors
genome wide
early onset
case report
copy number
childhood cancer