Systematic review with meta-analysis: the efficacy and safety of tenofovir to prevent mother-to-child transmission of hepatitis B virus.

Myung Han HyunY-S LeeJ H KimJ H JeY J YooJ E YeonK S Byun

Published in: Alimentary pharmacology & therapeutics (2017)

For pregnant women with high hepatitis B virus DNA levels, tenofovir administration in the second or third trimester can prevent mother to child transmission when combined with hepatitis B immunoglobulin and the hepatitis B vaccine. Tenofovir is safe and tolerable for both the mother and foetus.

Keyphrases

hepatitis b virus
pregnant women
antiretroviral therapy
mental health
liver failure
pregnancy outcomes
circulating tumor
cell free
preterm birth
nucleic acid