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Real-life clinical use of natalizumab and fingolimod in Austria.

Michael GugerC EnzingerF LeutmezerJörg KrausS KalcherE KvasT Berger
Published in: Acta neurologica Scandinavica (2017)
The generalized linear model (GLM) for relapse count as Poisson distributed dependent variable and propensity score as covariate showed a statistically significant reduction for the mean relapse count in the natalizumab group compared with fingolimod. This effect was smaller in the analyses of log-transformed ARR with propensity score matching, loosing statistical significance although showing the same direction for the effect. We assume that the GLM was the more sensitive model analysing this question.
Keyphrases
  • multiple sclerosis
  • free survival
  • peripheral blood