Early putamen hypertrophy and ongoing hippocampus atrophy predict cognitive performance in the first ten years of relapsing-remitting multiple sclerosis.

Maria Elisa MorelliSara BaldiniArianna SartoriLaura D'AcuntoAlessandro DinotoAntonio BoscoAlessio BratinaPaolo Manganotti

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2020)

In the first years of RRMS, putamen hypertrophy and hippocampus atrophy could represent promising indices of cognitive performance and reserve, and become potentially useful tools for diagnostic, prognostic, and therapeutic purposes.

Keyphrases

multiple sclerosis
white matter
prefrontal cortex
cerebral ischemia
cognitive impairment
disease activity
rheumatoid arthritis
brain injury